Sequence 1 (CSK , EGFR , EPHA8 , ERBB2 , ERBB4 , FLT3 , JAK1 , SRMS ( Homo sapiens ))

Sequence CSK , EGFR , EPHA8 , ERBB2 , ERBB4 , FLT3 , JAK1 , SRMS ( Homo sapiens )
Target	CSK , EGFR , EPHA8 , ERBB2 , ERBB4 , FLT3 , JAK1 , SRMS ( Homo sapiens )
Description	ENSG00000103653 15:74782057-74803198:1 C-src tyrosine kinase ; ENSG00000146648 7:55019021-55256620:1 Epidermal growth factor receptor ; ENSG00000070886 1:22563564-22603594:1 EPH receptor A8 ; ENSG00000141736 17:39687914-39730426:1 Erb-b2 receptor tyrosine kinase 2 ; ENSG00000178568 2:211375717-212538841:-1 Erb-b2 receptor tyrosine kinase 4 ; ENSG00000122025 13:28003274-28100592:-1 Fms-related tyrosine kinase 3 ; ENSG00000162434 1:64833229-64966504:-1 Janus kinase 1 ; ENSG00000125508 20:63540810-63547504:-1 Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
Design	peptide
Chemistry	amino
Sequence	VHRDLAARNVLV
Application	multitargeting
Name	CSK , EGFR , EPHA8 , ERBB2 , ERBB4 , FLT3 , JAK1 , SRMS ( Homo sapiens )

References

Identification of sequences common to more than one therapeutic target to treat complex diseases: simulating the high variance in sequence interactivity evolved to modulate robust phenotypes. Varela MA. BMC Genomics. 2015 Jul 18;16(1):530.

Intrathecal Injections in Children With Spinal Muscular Atrophy: Nusinersen Clinical Trial Experience. Hache M, Swoboda KJ, Sethna N, Farrow-Gillespie A, Khandji A, Xia S, Bishop KM. J Child Neurol. 2016 Jun;31(7):899-906. PubMed:26823478

Comments

Not experimentally validated

Background